In case of erectile dysfunction, it is better to take sildenafil on an empty stomach. It may take longer to work if you take it with food. Accidentally taking too much sildenafil can cause unpleasant side effects, such as: In the early 1990s, while experimenting with sildenafil as a possible treatment for angina pectoris (a form of chest pain caused by poor blood flow to the heart), a team of Pfizer researchers found that many volunteers reported erections as a side effect of the new drug. There are also oral spray preparations of sildenafil for a faster onset of action. If the pharmacist has concerns about whether sildenafil is safe for you, they may advise you to consult your doctor. Rare but serious side effects identified by post-marketing surveillance include prolonged erections, severe blood pressure, myocardial infarction (heart attack), ventricular arrhythmias, stroke, increased intraocular pressure and sudden hearing loss. [4] In October 2007, the FDA announced that labeling all PDE5 inhibitors, including sildenafil, requires a clearer warning about the potential risk of sudden hearing loss. [25] There is no strong evidence that sildenafil works in women with sexual problems. 18.
Night fog A, Stöllberger C, Ehrlich M, Darth J. Aortic dissection after erection induced by sildenafil. South Med J. (2006) 99:1151–2. doi: 10.1097/01.smj.0000240732.65859.aa In the United States, the brand name Viagra and its generic version Sildenafil are only sold to people with a valid prescription. Although sildenafil improves some markers of disease in people with pulmonary arterial hypertension, it does not appear to affect the risk of death or serious side effects. [18] You can eat and drink normally while taking sildenafil (Viagra) to get an erection. These side effects are rare, and most men are able to use Viagra and other drugs for erectile dysfunction without significant problems. Our Viagra side effects guide provides more information about the problems that can occur with Viagra and generic sildenafil. People who are also taking protease inhibitors to treat HIV infection should be careful. Protease inhibitors inhibit sildenafil metabolism, effectively multiply plasma sildenafil levels, and increase the frequency and severity of side effects. Those using protease inhibitors are advised to limit their use of sildenafil to a maximum dose of 25 mg every 48 hours.
[4] Other drugs that interfere with the metabolism of sildenafil include erythromycin and cimetidine, which may also result in a prolonged plasma half-life. [26] Sildenafil liquid is usually prepared for you by your pharmacist. There is no clear evidence that taking sildenafil reduces fertility in women or men. Consult your doctor before taking sildenafil if you: You should be able to get an erection anytime between 1 and 4 hours after taking sildenafil. While all drugs have some expected side effects, a drug manufacturer has a duty to make their products as safe as possible and to inform the medical community and the public of the known risks associated with their medications. If a manufacturer fails to do so, they can be held legally liable if patients are injured due to inadequate warnings or the unreasonable dangerousness of the drug, according to a legal theory known as “product liability.” Tell your doctor if you are taking these medicines before starting sildenafil: The 2007 Ig Nobel Prize in Aviation was awarded to Patricia V. Agostino, Santiago A. Plano and Diego A. Golombek of the Universidad Nacional de Quilmes, Argentina, for their discovery that sildenafil helps treat jet lag recovery in hamsters. [35] [36] In 1992, Pfizer filed a patent application for the substance sildenafil and its use in the treatment of cardiovascular disease. [108] This substance would be in commerce as Revatio.
The patent was published in 1993 and expired in 2012. The patent on Revatio (indicated for pulmonary arterial hypertension and not for erectile dysfunction) expired at the end of 2012. Generic versions of this low-dose form of sildenafil were available in the United States. from a number of manufacturers, including Greenstone, Mylan and Watson, since early 2013. [109] Health care providers may prescribe generic sildenafil for erectile dysfunction. [106] However, generic is not available in the same doses as branded Viagra, so using the doses typically required for the treatment of erectile dysfunction requires patients to take multiple pills. [106] Created by FindLaw`s team of writers and legal writers| Last updated: 04 December 2018 You can buy Sildenafil / Viagra on the Internet.